Standard difficulty · 20 questions · 40 marks
Show your working for Sections B and C. Answers are on the last page — try every question first!
Human Reproduction · AW-12B-HRP-2026-V1 · For parents — fold back or tear off before handing the sheet to your child.
| Q | Answer | Working |
|---|---|---|
| 1 | (d) about 2–2.5 °C below body temperature | — |
| 2 | (a) 23 | haploid, after meiosis I |
| 3 | (c) 490 | each primary oocyte gives one ovum and polar bodies |
| 4 | (d) exchange of food, oxygen and wastes between mother and foetus | — |
| 5 | (a) relaxin | — |
| 6 | (c) at about nine months | — |
| 7 | (c) day 14 | the luteal phase lasts about 14 days, so ovulation is about 14 days before the next period |
| 8 | (c) A is true, but R is false. | A is true: each primary oocyte gives one ovum; the other products are polar bodies. R is false. |
| 9 | It is a cap on the sperm head containing enzymes that help the sperm penetrate the layers around the ovum. | — |
| 10 | 147.6 million normal; 98.4 million vigorously motile | 60% and 40% of 246 million |
| 11 | 1,200 sperms; 300 ova and 900 polar bodies | spermatogenesis: 4 per cell; oogenesis: 1 ovum + 3 polar bodies |
| 12 | 32 cells; 3 divisions; a morula has 8 to 16 cells | each division doubles the number: 25 = 32 and 23 = 8 |
| 13 | day 16; follicular (proliferative) phase from day 6 to day 15, mainly oestrogen; luteal (secretory) phase from day 17 to day 30, mainly progesterone | the luteal phase lasts about 14 days |
| 14 | Oestrogen: builds up the endometrium in the follicular phase; prolactin: stimulates milk production | — |
| 15 | a Leydig cell: 46, diploid; a primary spermatocyte: 46, diploid | meiosis I halves the number |
| 16 | (a) during the fifth month; (b) implantation of the blastocyst | — |
| 17 | In the seminiferous tubules, spermatogonia (2n) divide by mitosis; some grow into primary spermatocytes (2n), which complete meiosis I to form secondary spermatocytes (n) and then meiosis II to form spermatids (n), which change into sperms (spermiogenesis). GnRH from the hypothalamus causes LH and FSH release: LH makes Leydig cells secrete androgens, which drive spermatogenesis; FSH acts on Sertoli cells, which help spermiogenesis. | — |
| 18 | Spermatogenesis: 800 sperms; no polar bodies; spermatogonium and primary spermatocyte 46, secondary spermatocyte, spermatid and sperm 23; in the seminiferous tubules, continuously from puberty. Oogenesis: 200 ova; up to 600 polar bodies; oogonium and primary oocyte 46, secondary oocyte and ovum 23; in the ovary, begun before birth, completed only after fertilisation | — |
| 19 | Menstrual phase (days 1–4 or 5): the endometrium breaks down. Follicular phase (to about day 16): FSH grows follicles, which secrete oestrogen that rebuilds the endometrium. Ovulation about day 17: triggered by the LH surge. Luteal phase (days 18–31): the corpus luteum secretes progesterone to keep the endometrium ready. Without fertilisation the corpus luteum degenerates, progesterone falls and menstruation starts again | — |
| 20 | Fertilisation in the ampulla forms the zygote (46). It divides by cleavage as it moves down the oviduct: after 5 divisions it has 32 cells, and 128 cells need 7 divisions; at 8–16 cells it is a morula, which becomes a blastocyst with an outer trophoblast and an inner cell mass. The trophoblast attaches to the endometrium and the blastocyst becomes embedded (implantation); the inner cell mass becomes the embryo | — |